Talipexoledihydrochloride(#B-140) isahighlypure,synthetic,andbiologicallyactivecompound.
LyophilizedPowderThisproductisfreezedried.Allwatermoleculeshavebeenremoved.
BioassayTestedEverylotistried&testedinarelevantBIOLOGicalassay.
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Talipexoleisanazepinederivative,andactsasanagonistofD2dopaminepre-andpostsynapticreceptors,aswellasan α2-adrenoceptoragonistand5-HT3receptorantagonist1.
ThepurposeofTalipexoleistoincreasedopamineactivityinthecentralnervoussystem.ItinhibitselectricallyevokedreleaseofdopaminethroughactivationofD2synapticautoreceptorslocatedondopaminergicterminals.Italsocausesreleaseofacetylcholineandnoradrenalin2,3.
Talipexolehasbeenestablishedinanumberofclinicaltrialsasananti-Parkinsonianagent.Thesetrialsshowedsignificantimprovementinmotoractivityandinotherparkinsoniansymptomsincludingakinesia,rigidity,tremorandgaitdisturbances.Thereareseveralsideeffectscausedbythisdrugsuchasdrowsiness,dizziness,hallucinations,gastrointestinaldiscomfort,nauseaandlossofappetite3.
Inaddition,talipexoleisalsoexpectedtobebeneficialforthetreatmentofperiodiclegmovementdisorderandrestlesslegsyndrome4.
Talipexoledihydrochloride(#B-140) isahighlypure,synthetic,andbiologicallyactivecompound.
Discoveryantibodies
CRB是世界上第二大肽公司,也是抗体研究市场的先驱,它现在正在探索抗体的旗帜下建立一批新验证的目标抗体。
CRB, the 2nd oldest peptide company in the world and forerunner in the antibody research market is now building a collection of newly validated target antibodies under the banner of Discovery® Antibodies.
品牌 | 货号 | 名称 | 规格 |
Discoveryantibodies | crb2005253 | Anti-crc antibody | 20ul 100ul |
Discoveryantibodies | crb2005041 | Anti-IL-11 antibody | 20ug 100ug |
Discoveryantibodies | crb2005038 | Anti-RAMP1 antibody | 20ug 100ug |



