trans-ACBD(#A-280) isahighlypure,synthetic,andbiologicallyactivecompound.
Thisproductisfreezedried.Allwatermoleculeshavebeenremoved.
Everylotistried&testedinarelevantBIOLOGicalassay.
OurBioassay
trans-ACBDisapotent,competitiveandselectiveactivatorofglutamateuptake.ThecompoundactsasanNMDA(N-methyl-D-aspartate)receptoragonist.TheACBDstructureincludestwoisomers:cis-1-aminocyclobutane-1,3-dicarboxylicacidandtrans-1-aminocyclobutane-1,3-dicarboxylicacid.Severalstudieshaveshownthatthetransisomerismorepotentthanthecisisomer.Thetransisomerwasalsoshowntobe20timesmoreactivethanNMDA1,2,themajorexcitatoryneurotransmitterinthemammaliancentralnervoussystem(CNS).
SeveralstudiessuggestthatmodificationsandchangesofglutamateuptakecouldplayaroleinprocessesunderlyingsynapticplasticityintheCNS2.
NMDAreceptorsareionchannelsgatedbyglutamate.Glutamate-mediatedsignalingisimportantforbasicneuron-neuronsignalingandneuronalprocessessuchaslearning,memoryandpainperception3.
trans-ACBD(#A-280) isahighlypure,synthetic,andbiologicallyactivecompound.
Discoveryantibodies
CRB是世界上第二大肽公司,也是抗体研究市场的先驱,它现在正在探索抗体的旗帜下建立一批新验证的目标抗体。
CRB, the 2nd oldest peptide company in the world and forerunner in the antibody research market is now building a collection of newly validated target antibodies under the banner of Discovery® Antibodies.
品牌 | 货号 | 名称 | 规格 |
Discoveryantibodies | crb2005253 | Anti-crc antibody | 20ul 100ul |
Discoveryantibodies | crb2005041 | Anti-IL-11 antibody | 20ug 100ug |
Discoveryantibodies | crb2005038 | Anti-RAMP1 antibody | 20ug 100ug |